A recent study conducted by Duke University Medical Center in the United States has found that men exposed to cannabis or Tetrahydrocannabinol (THC) during their reproductive years experience changes in the genetic profile of their sperm.

The research also highlighted that several external factors, such as tobacco smoke, pesticides, flame retardants, and obesity, can affect sperm by causing epigenetic changes. Epigenetics are heritable traits that do not alter DNA sequencing but result from life experiences.

The study, which involved 24 men, revealed that THC affects epigenetics, leading to structural and regulatory modifications in sperm DNA. Specifically, THC targets genes in two key cellular pathways, altering DNA methylation, a crucial process for normal development.

Scott Kollins, a senior author and Professor of Psychiatry and Behavioral Sciences, stated, “Our findings show that cannabis use impacts the genetic profile of sperm in males.” Co-author Susan Murphy, an Associate Professor, added that while the study shows changes in sperm DNA, it remains unclear if these changes can be passed on to future generations.

Murphy advised that, until further research is conducted, it’s best to assume these changes exist and recommended stopping cannabis use at least six months before attempting to conceive.

The News Agency of Nigeria (NAN) explains that cannabis, also known as marijuana, refers to the dried leaves, flowers, stems, and seeds of the THC plant, which contains chemicals that alter the mind and similar compounds.